The Gene Expression Response of Breast Cancer to Growth Regulators: Patterns and Correlation with Tumor Expression Profiles

Heather E. Cunliffe, Markus Ringnér, Sven Bilke, Robert L. Walker, Jennifer M. Cheung, Yidong Chen, and Paul S. Meltzer1


Cancer Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland 20892 [H. E. C., R. L. W., J. M. C., Y. C., P. S. M.]; Complex Systems Division, Department of Theoretical Physics, Lund University, SE-223 62 Lund, Sweden [M. R.]; and Advanced Technology Center, National Cancer Institute, Gaithersburg, Maryland 20877 [S. B.]


CANCER RESEARCH · VOLUME 63 · 7158-7166 · NOVEMBER 2003


Supplemental information:

  1. Article

    Cunliffe et al.pdf (PDF file)

  2. Supplementary Figures and tables

    Supplementary Fig.1.pdf (PDF file)
    [List of 386 hormonally regulated genes from Fig. 3].

    Supplementary Fig 2.pdf (PDF file)
    [List of 714 genes regulated in kinase signaling from Fig. 4].

    Supplementary Fig 3.pdf (PDF file)
    [List of 1023 genes regulated across all treatment conditions. Included are the positions of genes predictive for ER status and poor prognosis (van't Veer et al, Nature, 415: 530-536, 2002).

    Supplementary Table 1.pdf (PDF file)
    [List of genes corresponding to Gene Ontology peaks from Fig. 6]

  3. Supplemental Data

    Supplementary data.xls (XLS file)
    [ratio expression data for all 1023 genes shown and ordered as in Figure 5].



Supplementary information for Javed Khan, et. al, Nature Medicine, 7(6):673-679, 2001.


The Nature Medicine paper: Classification and diagnostic prediction of cancers using gene expression profiling and artificial neural networks is available here.

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