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Genometric Analysis Simulation Program (GASP)
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Traits
- A quantitative trait is produced as a normally distributed variate
with mean 0 and variance 1. The user may choose to adjust the location
and/or scale in the driver.
- A qualitative trait can be generated directly as a "marker"
locus or indirectly (in the driver), using a quantitative trait as an underlying
genetic liability.
- A trait is determined by a list of its components, with the corresponding
proportion of the total phenotypic variance attributed to each.
- Traits can share components, enabling models with pleiotropy and other
complex situations.
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Comments, suggestions and problems to
bioinformatics@nhgri.nih.gov
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